Strontium ranelate incorporated 3D porous sulfonated PEEK simulating MC3T3-E1 cell differentiation
نویسندگان
چکیده
منابع مشابه
Polymeric strontium ranelate nonahydrate
The title compound, poly[[μ-aqua-tetra-aqua{μ-5-[bis-(carboxyl-atometh-yl)amino]-3-carboxyl-atomethyl-4-cyano-thio-phene-2-carboxyl-ato}distrontium(II)] tetra-hydrate], [Sr(2)(C(12)H(6)N(2)O(8)S)(H(2)O)(5)]·3.79H(2)O, crystallizes with nine- and eight-coordinated Sr(2+) cations. They are bound to seven of the eight ranelate O atoms and five of the water mol-ecules. The SrO(8) and SrO(9) polyhed...
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Protein kinase C (PKC) is a family of kinases whose isoforms show subtle differences in physiological and biochemical responses, with their expression being cell- specific. We hypothesize that there may be a specific profile of expression of PKC isoforms in differentiating osteoblastic cells (OBC) with individual isoforms having specific functions. Herein, the MC3T3-E1 cell line was used as a d...
متن کاملAction mechanism of strontium ranelate
Characteristics of strontium Strontium was discovered in 1790 in a mine close to the Scottish village Strontian and was isolated in 1808. Strontium is one of the alkaline earth metals and is never found in its free form in nature because it easily oxidises, forming strontium oxide. Strontium, along with calcium and magnesium belongs to group 2 of the periodic table which are divalent cations, w...
متن کاملOsteoblastic cell adhesion on Strontium-incorporated porous nanostructured TiO2 coating prepared by micro-arc oxidation
Objective: In the present work, strontium (Sr) was incorporated into TiO2 (Sr-TiO2) coatings on titanium by Micro-arc oxidation (MAO) technique in the Ca, P, Sicontaining electrolyte to obtain the implant with good bioactivity. Methods: The surface topography, phase and element composition were characterized by scanning electron microscopy, X-ray diffraction and energy dispersive spectrometer, ...
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Osteoporosis is a disease in which the microarchitecture of bone tissue deteriorates, with consequent loss of bone mass. Strontium ranelate (SrR) is currently used for treatment of the condition. SrR may have a dual effect: anabolic (stimulating pre-osteoblast replication) and anti-catabolic (reducing osteoclastic activity). However, its mechanism of action has not yet been completely elucidate...
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ژورنال
عنوان ژورنال: Regenerative Biomaterials
سال: 2020
ISSN: 2056-3418,2056-3426
DOI: 10.1093/rb/rbaa043